Haploid and Diploid Cells (Advanced Concepts)

Concept sheet | Science and Technology
Table of contents
Be careful!
Definitions
  • The term haploid describes an organism, cell or cell nucleus that contains only one set of chromosomes.

  • The term diploid describes an organism, a cell or the nucleus of a cell that contains two sets of chromosomes.

Important!

The symbol |\bf \text{n}| means haploid. The value of |\text{n}| corresponds to a number of chromosomes and varies from one species to another.

The symbol |\bf \text{2n}| means diploid. The value of |\text{2n}| corresponds to the doubled value of |\text{n}.|

In humans, |\text{n}=23| chromosomes and |\text{2n}=46| chromosomes because |2\times23=46.|

The number of chromosomes in haploid (n) and diploid (2n) cells is as follows: 6 and 12 in houseflies, 8 and 16 in western grey kangaroos, 19 and 38 in domestic cats, 23 and 46 in humans and 24, and 48 in chimpanzees.

The number of chromosomes in haploid and diploid cells in some animal species

The number of chromosomes in haploid (n) and diploid (2n) cells is as follows: 6 in penicillium fungus (haploid organism), 16 and 32 in brewer’s yeast, 17 and 34 in crab apples, 23 and 46 in olives, and 25 and 50 in pineapples.

The number of chromosomes in haploid and diploid cells in some species of fungi and plants

Examples

Examples of human diploid cells are skin epithelial cells, neurons, muscle cells and zygotes. There are 46 chromosomes in their nuclei.

Skin cells, neuron, muscle cells and zygote.
Examples

The oocyte (immature ovum) and the spermatozoon are called reproductive cells or gametes. These gametes are the only haploid cells in the human body. The female reproductive system produces the oocyte during oogenesis, and the male reproductive system produces the spermatozoa during spermatogenesis. Gametes are used only for sexual reproduction and have 23 chromosomes in their nuclei.

An oocyte and a spermatozoon.

Humans are therefore diploid organisms that produce haploid gametes. The human development cycle is characterized by a very long diploid period and a very short haploid period.

These are the stages of the human development cycle:

  1. Two haploid |(\text{n})| gametes combine during fertilization and form a diploid zygote  |(\text{2n}).|

  2. Through mitosis, the zygote grows and develops until the end of adolescence.

  3. Through meiosis, the reproductive system produces haploid gametes |(\text{n})| that could participate in fertilization. A new cycle begins.

During fertilization, two haploid gametes combine to form a diploid zygote. This zygote initiates the first of many cycles of mitosis, enabling growth and development into an embryo, a fetus, a child and, eventually, an adolescent, who will start producing haploid gametes through meiosis at puberty.

The human development cycle

In the previous picture, the haploid phase of the human development cycle is very short. This is not the case for all species. Many species have haploid and diploid phases that are quite different from humans. For example, the development cycle of sea lettuce is shown here.

Alternating Diploid and Haploid Generations in Sea Lettuce